Scoring systems for heparin-induced thrombocytopenia (HIT): whither now?
نویسنده
چکیده
3535.18. Leroux D, Hezard N, Lebreton A, et al. Prospectiveevaluation of a rapid nanoparticle-based lateralflow immunoassay (Stic Expert® HIT) for the diag-nosis of heparin-induced thrombocytopenia. Br JHaematol 2014; 166: 774-782.19. Warkentin TE, Sheppard JI, Moore JC, et al. Quanti-tative interpretation of optical density measure-ments using PF4-dependent enzyme-immunoas-says. J Thromb Haemost 2008; 6: 1304-1312.20. Raschke RA, Curry SC, Warkentin TE, et al. Improved clinical interpretation of the anti-plateletfactor 4/heparin enzyme-linked immunosorbentassay for the diagnosis of heparin-induced throm-bocytopenia through the use of receiver operatingcharacteristic analysis, statum-specific likelihoodratios, and Bayes theorem. Chest 2013; 144:1269-1275.Invited Editorial Focus For personal or educational use only. No other uses without permission. All rights reserved.Downloaded from www.thrombosis-online.com on 2017-04-08 | IP: 54.191.40.80
منابع مشابه
Heparin induced thrombocytopenia
Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...
متن کاملClinical and laboratory diagnosis of heparin-induced thrombocytopenia: an integrated approach.
Heparin-induced thrombocytopenia (HIT) is a clinicopathologic disorder that predisposes to thrombosis. Diagnosis rests on a compatible clinical picture and laboratory evidence of antiplatelet factor 4 (PF4)/heparin antibodies that activate platelets in a heparin-dependent manner. Rapid and accurate diagnosis is paramount to avoid the perils of misdiagnosis. Clinical evaluation may be guided by ...
متن کاملClinical Presentation and Evaluation of the Utility of the 4T Scoring System in the Diagnosis of Heparin Induced Thrombocytopenia among Patients at Sultan Qaboos University Hospital
The use of heparin have increased in the last years in hospitalized both as prophylaxis and therapeutic. One of the encounter complications of heparin especially with unfractionated heparin though it can be seen with Low molecular weight heparin is thrombocytopenia which could be transient non immune or more badly the immune mediated type heparin induced thrombocytopenia (HIT). Heparin-induced ...
متن کاملClinical Presentation and Evaluation of the Utility of the 4T Scoring System in the Diagnosis of Heparin Induced Thrombocytopenia among Patients at Sultan Qaboos University Hospital
The use of heparin have increased in the last years in hospitalized both as prophylaxis and therapeutic. One of the encounter complications of heparin especially with unfractionated heparin though it can be seen with Low molecular weight heparin is thrombocytopenia which could be transient non immune or more badly the immune mediated type heparin induced thrombocytopenia (HIT). Heparin-induced ...
متن کاملEvaluating heparin-induced thrombocytopenia: the old and the new.
Heparin-induced thrombocytopenia (HIT) is a rare but potentially serious complication of heparin use. Prompt diagnosis is crucial and requires the integration of clinical assessment and laboratory testing. Pretest clinical scoring systems (i.e., 4 Ts) have been established. Immunoassays can detect the presence of antibodies directed toward heparin-platelet factor 4 (H-PF4) complexes, but provid...
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عنوان ژورنال:
- Thrombosis and haemostasis
دوره 113 3 شماره
صفحات -
تاریخ انتشار 2015